Existing tools and guidance on Multipurpose Cash Assistance (MPCA) generally focus on the technical approach to achieving sectoral outcomes. However, this presumes levels of integration between and among sectors that remains a challenge due to a myriad of reasons. Based on the lessons learnt from Colombia, Peru, Nicaragua, and Guatemala’s experience with MPCA and sectoral integration, the aim of this document is to provide humanitarian staff with a practical guide on what to consider when designing MPCA programmes whilst ensuring intersectoral collaboration and integration.