This Briefing aims to contribute to the debate on the M&E of SSC, using the Brazilian SSC as a starting point. The issues discussed here draw from the authors’ own experience evaluating Brazilian cooperation initiatives and further explore some issues raised during the event “Dialogues on South-South Cooperation”. We outline some reflections on SSC M&E, more specifically on South-South technical cooperation (SSTC), considering: The central object of these initiatives, namely, their capacity development focus; The unfolding of SSC principles during initiatives’ implementation and suggestions for their operationalization in M&E; Challenges related to planning and management tools and their implications for M&E; Final considerations on possible pathways to strengthen M&E practices.